Need strong short-term pain relief? Ketorolac, often sold as Toradol, is a potent NSAID doctors use for moderate-to-severe acute pain—think post-surgery, kidney stones, or a bad injury. It works by blocking pain-and-inflammation chemicals in the body. Unlike opioids, it doesn’t cause breathing depression, but it brings its own risks that matter.
Ketorolac comes in IV, IM, and oral forms. Hospitals commonly give a single IV or IM dose (often 30 mg for adults) and may switch to oral 10 mg tablets for continued relief. Total use should be short: a typical rule is no more than 5 days of combined parenteral and oral therapy. That limit lowers the chance of serious side effects like bleeding or kidney damage.
Typical dosing looks like this: a one-time IV/IM dose (commonly 30 mg) or 15 mg for older adults or those underweight, then oral 10 mg every 4–6 hours as needed up to 40 mg per day. Always follow the exact instructions your provider gives—doses can change with age, weight, and kidney function.
Don’t use ketorolac if you already have active stomach ulcers, recent gastrointestinal bleeding, severe kidney disease, or if you’re near delivery (third-trimester pregnancy). It raises the risk of serious gastrointestinal bleeding, ulcers, and kidney injury—risks that increase with longer use, higher doses, and with alcohol or blood thinners.
Avoid combining ketorolac with other NSAIDs (ibuprofen, naproxen) or with anticoagulants unless your doctor specifically approves it. Also be cautious if you take SSRIs or SNRIs—they can raise bleeding risk when mixed with NSAIDs. Tell your provider about all meds, supplements, and if you drink alcohol regularly.
Watch for warning signs: black or bloody stools, severe stomach pain, unexpected bruising or bleeding, swelling, shortness of breath, or reduced urine output. If any of those happen, stop the drug and seek medical help.
Older adults need extra caution. Doctors often use lower doses or choose different pain relief because the elderly are more likely to have kidney or stomach issues that ketorolac can worsen.
If you have mild pain or long-term pain, ketorolac is not a good choice. It’s meant for short bursts only. For chronic pain, your provider will usually recommend safer long-term options like acetaminophen, topical meds, physical therapy, or other NSAIDs used carefully.
Final practical tips: use the lowest effective dose for the shortest time, avoid alcohol, tell your clinician about all health issues and meds, and don’t self-prescribe. If you’re unsure whether ketorolac is right for you, ask your healthcare provider—especially if you have heart, kidney, or stomach problems.
In my latest blog post, I explored the role of Ketorolac in pain management. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for short-term pain relief. I discovered that it's particularly effective in treating moderate to severe acute pain, often following surgery. However, it's important to note that Ketorolac should be used cautiously, as it can cause serious side effects such as gastrointestinal bleeding and kidney damage. Overall, Ketorolac can be a useful tool in managing pain, but it's essential to follow proper guidelines and consult with a healthcare professional.
Health and Medicine