Celexa (citalopram): what you need to know

Celexa is the brand name for citalopram, a commonly prescribed SSRI used to treat depression and some anxiety disorders. If you're starting it or thinking about it, you probably want straightforward answers: how fast it works, what side effects to expect, and what to watch for. Below I cover the key facts in plain language so you can talk with your doctor or pharmacist with confidence.

How Celexa works and typical dosing

Citalopram increases serotonin in the brain, which can lift mood and reduce anxiety over time. Many people notice some change within 2–4 weeks, but full benefit can take 6–8 weeks. Typical starting dose for adults is 20 mg once a day. Doctors may raise it to 40 mg daily if needed. For people over 60, with liver problems, or taking certain medicines that interfere with its breakdown, doctors often limit the dose to 20 mg daily because of heart rhythm risks.

Common side effects, safety, and practical tips

Common side effects: nausea, dry mouth, sleep changes (insomnia or sleepiness), increased sweating, and sexual side effects (lower libido or trouble reaching orgasm). Most side effects get better after the first few weeks. If something feels severe or lasts, call your prescriber.

Citalopram can affect heart rhythm at higher doses. If you have heart disease, take other QT-prolonging drugs, or low potassium/magnesium, your doctor may order an ECG or choose a different antidepressant. Avoid mixing Celexa with MAO inhibitors; you usually need a 14-day gap between stopping one and starting the other to prevent serotonin syndrome.

Speaking of serotonin syndrome: if you combine Celexa with other serotonin-boosting drugs (like some migraine meds, tramadol, other antidepressants, or MDMA), watch for agitation, high fever, rapid heart rate, or severe shaking. That’s rare but needs urgent care.

Don’t stop Celexa abruptly. Stopping suddenly can cause withdrawal-like symptoms—dizziness, irritability, flu-like feelings, insomnia. If you plan to stop, ask your clinician about a taper plan. Also avoid heavy drinking while on Celexa; alcohol can worsen mood and side effects.

Quick practical tips: take the pill at the same time every day; if it makes you sleepy, take it at night, if it keeps you awake take it in the morning. If you miss a dose, take it when you remember unless it’s almost time for the next one—don’t double up. Keep regular follow-ups in the first 6–8 weeks so your doctor can track response and safety.

If you feel worse, have new suicidal thoughts, or notice severe side effects, seek help right away. Celexa helps many people, but it needs monitoring and clear communication with your care team. Ask questions, keep a symptom log, and don’t hesitate to bring up sexual side effects or sleep problems—they’re fixable with dose changes or switching meds.